What is the project about?
The Bump2Baby and Me project is a five-year study focused on supporting women and their babies during and after pregnancy with healthy eating, being active and getting children off to the best start in life. At the heart of the study is a trial to test an innovative healthcare intervention with the aim of delivering implementable solutions for hospitals and health service providers.
The main objective of the Bump2Baby and Me project is to contribute to the early prevention of maternal and child diabetes, overweight and obesity and other non-communicable associated diseases, which include hypertension, cardiovascular diseases, metabolic syndrome, cognitive deficits, and behavioural issues.
Why does it matter?
of pregnancies have obesity or overweight issues* 
of pregnancies affected by gestational diabetes (GDM)* 
more likely for mothers to develop type 2 diabetes if had GDM* 
increased risk of early childhood overweight or obesity where mothers' had GDM* 
How will it work?
The main implementation trial (Trial registration: ACTRN12620001240932) is an international, multicentre, complex randomised controlled trial (RCT). The RCT is going to run in maternity hospitals in Ireland, the UK, Spain and Australia (Dublin, Bristol, Granada and Melbourne). It will assess the effectiveness and cost-efficiency of a low-cost health coaching lifestyle behaviour change app on weight and health outcomes for both mother and child through pregnancy and the first year following birth. The main trial will focus on working with women who are identified at high risk of gestational diabetes and who will therefore benefit most from this behaviour change intervention.
Who is involved?
The consortium is led by University College Dublin and involves nine partners from five countries. It brings together world-leaders in maternal and child health alongside a cutting-edge mobile health technology company. The expertise across the partners covers implementation science, clinical practice, mobile health, public health nutrition, health psychology, health economics, biostatistics, complex intervention design and communications.
The project also has an External Advisory Board (EAB), established to provide independent scientific, policy and ethics advice and support to the consortium. The EAB members are:
- Professor Molly Byrne, National Universities of Ireland Galway;
- Dr Fionnuala Gough, Trinity College Dublin;
- Professor Helen Murphy, Kings College London;
- Professor Ciaran O’Neill, Queen’s University Belfast;
- Dr Rupert Suckling, Doncaster Council.
Work packages (WPs)
WP1 - Intervention optimisation
This work package will perform a systematic scoping review to identify and deconstruct effective interventions, including examining the cost effectiveness of the interventions. The review will consider other apps or programmes which are already in the marketplace and develop an understanding of how they have been implemented and how effective they are. This work will guide the mapping and classification of behaviour change to enable the development of an optimised framework for postnatal intervention.
Partners involved: Monash University (Lead), University College Dublin, University of Copenhagen.
WP2 - App and health coaching library co-creation
Work package 2’s main output will be to deliver a tailored and co-created Bump2Baby and Me app in both English and Spanish. The co-creation will be done with input from key stakeholders in each country (Australia, Ireland, Spain, and UK). The app will include content and a health coach manual, and inter-country differences such as guidelines and local practices.
Partners involved: Liva Healthcare (Lead), Aarhus University, Monash University, University of Bristol, University of Copenhagen, University of Granada.
WP3 - Implementation planning
The objectives of work package 3 are to identify and map the external contextual factors that influence both gestational weight gain and gestational diabetes (GDM) management for each trial site; and to identify the use of GDM risk screening tools and GDM mHealth technology across each site.
Information from work package 1 will guide the mapping work and this work will inform work packages 4 and 5.
Partners involved: University of Bristol (Lead), Monash University, University College Dublin, University of Granada.
WP4 - Training development and delivery
Work package 4 will develop and deliver two training systems: 1) A training system for healthcare staff to implement the GDM screening tool within EU sites; 2) A health coaching training programme for working with women during their infants’ first 1,000 days. Recruitment of health coaches and evaluation of the intervention delivery are also included in WP4.
Partners involved: University of Copenhagen (Lead), Liva Healthcare, North Bristol NHS Trust, University College Dublin, University of Bristol, University of Granada.
WP5 - Implementation leadership
This work package will initiate the randomised controlled trial, ensuring it runs according to best ethical and trial procedures. The trial will begin at the Dublin site and will be subsequently rolled out across the other country sites in the UK, Spain and Australia. This will ensure maximum learning amongst sites.
Partners involved: University of Copenhagen (Lead), Liva Healthcare, Monash University, North Bristol NHS Trust, University College Dublin, University of Bristol, University of Granada.
WP6 - Implementation, cost-effectiveness and RCT evaluation
Work package 6 will drive the analysis plans and integration of findings into dissemination activities (WP8). It includes developing strategies for the analysis of outcomes, cost-effectiveness, data, and factors associated with the success of the intervention. It will also evaluate the results of the statistical analyses and the cost-effectiveness analysis, comparing results across settings.
Partners involved: University College Dublin (Lead), Aarhus University, Beta Technology, Deakin University, Liva Healthcare, Monash University, University of Bristol, University of Copenhagen, University of Granada.
WP7 - Project management
The aim of work package 7 is to ensure timely, effective and successful delivery of the project by providing a high level of administrative, contractual, financial and managerial support. The project is coordinated by Dr Sharleen O’Reilly from University College Dublin and supported by all partners.
WP8 - Dissemination, communication and exploitation
Work package 8 will ensure that the outcomes and achievements from the project are effectively transferred to end users and there is measurable uptake. This includes promotion of the project and its activities and results to a wide range of stakeholders, enabling knowledge transfer and innovation and maximising the project’s impacts. An implementation forum will be set up to guide and facilitate engagement with policymakers and healthcare decision makers throughout the project.
WP8 is led by Beta, supported by UCD and all other project partners.
WP9 - Ethics requirements
Work package 9 is responsible for monitoring the ethics and data privacy for the project. It will ensure that it follows the necessary criteria and procedures for ethics and the data is GDPR compliant. The ethics work package receives external and independent advice from the project’s External Advisory Board.
This work package is led by University College Dublin.
 CME Reynolds et al. Longitudinal Study of Maternal BMI in Successive Pregnancies. Obesity (2020), 28:460-467. doi:10.1002/oby.22707
 NCD Risk Factor Collaboration (2016). Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants. Lancet (2016), 387: 1513–30. doi: 10.1016/S0140-6736(16)00618-8
 E Vounzoulaki et al. Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis. BMJ (2020), 369. doi: 10.1136/bmj.m1361
 B Patro Golab et al. Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis. The Lancet Child & Adolescent Health (2018), 2(11):812-821.doi: 10.1016/S2352-4642(18)30273-6